Genome stability in crops
Genome integrity of cells is threatened by DNA damage caused by environmental and endogenous stresses. To cope with these stress conditions, cells have developed a set of surveillance mechanisms that monitor the status and structure of DNA during cell cycle progression. In fission yeast and mammals, DNA damage activates the signalling kinases ataxia telangiectasia mutated (ATM) and Rad3-related (ATR) that simultaneously turn on DNA repair complexes and arrest cell division, allowing cells to repair damaged DNA before proceeding into mitosis.